Alleviant ALLAY-HF Study
Conditions:
Heart Failure
Study Investigator:
Dr. Peter Eckman
About the Study:
Prospective, multicenter, randomized, sham-controlled, double blinded, adaptive study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with...
ALT-FLOW II
Conditions:
Heart Failure
Study Investigator:
Dr. Mike Samara
About the Study:
The objectives of this trial are to assess the safety, performance, and effectiveness of the Edwards APTURE transcatheter shunt system when used for the treatment of patients with heart failure with preserved (HFpEF) or mildly...
CORCINCH 5019
Conditions:
Heart Failure, Cardiomyopathy
Study Investigator:
Dr. Peter Eckman
About the Study:
Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction...
AIM HIGHer
Conditions:
Heart Failure
Study Investigator:
Drs. Mike Samara & Jay Sengupta
About the Study:
The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤60%.
OPTIMIZER PAS
Conditions:
Heart Failure
Study Investigator:
Dr. Jay Sengupta
About the Study:
The OPTIMIZER Smart Post-Approval Study is a prospective, multi-center, non-randomized, single arm open label study of 620 subjects receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA...
GenePHIT/ASK-CHF 2
Conditions:
Congestive Heart Failure
Study Investigator:
Dr. Jay Traverse
About the Study:
This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single dose of AB-1002, administered via antegrade intracoronary artery infusion, in...
Evolut EXPAND ll
Conditions:
Heart Valve Disease, Moderate Aortic Valve Stenosis
Study Investigator:
Dr. Paul Sorajja
About the Study:
Obtain safety and effectiveness data to support indication expansion for the Medtronic TAVR System to include patients with moderate, AS.
ALIGN AR
Conditions:
Heart Valve Disease, Aortic Regurgitation
Study Investigator:
Dr. Paul Sorajja
About the Study:
To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and...
AltaValve Pivotal Trial
Conditions:
Heart Valve Disease, Mitral Valve Regurgitation
Study Investigator:
Dr. Paul Sorajja
About the Study:
This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.
