Heart Rhythm Research

Joseph F. Novogratz Family Heart Rhythm Center

Our mission is to discover new ways to help patients with heart rhythm disorders live longer and better lives around the world.

Advancing Research and Care for Patients with Heart Rhythm Conditions

Heart rhythm disorders (arrhythmias) affect millions of people worldwide. The Joseph F. Novogratz Family Heart Rhythm Center is bringing new insights into the diagnosis and treatment of heart rhythm conditions. Under the leadership of Dr. Jay Sengupta, the Joseph F. Novogratz Family Heart Rhythm Center works to advance the prevention and treatment of heart arrhythmias such as atrial fibrillation and sudden cardiac arrest. This center also drives innovation through research of medical devices like pacemakers and implantable cardiac defibrillators (ICDs) that are important in the management of common heart rhythm conditions.

Through their extraordinary gift, the Novogratz family is making it possible for MHIF to advance care for future generations of families living with heart rhythm conditions.

Research Vision and Goals

Heart Rhythm Center

The vision: discover new ways to help patients with heart rhythm disorders live longer and better lives.

The goals:

  1. Save lives from sudden cardiac arrest.
  2. Improve quality of life for millions with atrial fibrillation.
  3. Improve patient safety of cardiac rhythm devices.
  4. Drive innovation for advanced understanding, treatment, and elimination of heart rhythm disorders worldwide.

About Heart Rhythm Research

We’re bringing new insights into the diagnosis and treatment of patients who are impacted by arrhythmias. In partnership with the Minneapolis Heart Institute®, one of the most comprehensive arrhythmia programs in the country, we conduct research on all types of heart rhythm disorders, ranging from those that are common to those that are rare and inherited.

Under the leadership of Dr. Jay Sengupta, MHIF researchers conduct cutting-edge research to improve and expand treatment options for patients with all types of heart rhythm disorders. As part of this work, researchers also monitor and analyze the safety and effectiveness of implantable cardiac devices. While the scope of heart rhythm conditions is broad, the different elements are interconnected. MHIF’s electrophysiology research team also works closely with MHIF’s heart failure and structural heart disease researchers, since many heart rhythm conditions often have associations with other heart conditions.

Research in Action

The Joseph F. Novogratz Family Heart Rhythm Center team focuses on these three key research areas:

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Sudden Cardiac Death Research

Sudden cardiac arrest (SCA) is a condition in which the heart suddenly and unexpectedly stops beating, usually as a result from a problem with the heart’s electrical system. When this happens, blood stops flowing to the brain and other vital organs, causing death if not treated within minutes.

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Atrial Fibrillation Research

Atrial fibrillation (AF) is the most common type of treated heart arrhythmias. AF causes the electrical signals of the heart to become chaotic and misfire. This can cause symptoms that severely limit a patient’s daily activities and increases their risk for stroke and heart failure.

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Cardiac Implantable Devices and Safety Research

Pacemakers and defibrillators are lifesaving technologies. MHIF researchers have expertise in promoting patient safety with these devices, including tracking safety and effectiveness of new devices and participating in research to advance the technologies and procedures.


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The Minneapolis Heart Institute Foundation® (MHIF) strives to create a world without heart and vascular disease. To achieve this bold vision, we are dedicated to improving the cardiovascular health of individuals and communities through innovative research and education.

Thanks to the generosity of donors like you, we can continue this life-saving work. Please make a gift to support the area of greatest need.

All Gifts Matched! Educating the Next Generation of Heart Heroes

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Since 2002, MHIF's Clinical Research Internship Program has hosted 235+ students for a unique physician-mentored cardiovascular research internship for undergraduate students. Interns not only gain exceptional experience that helps them prepare for medical school, they also help move MHIF research forward.

Community support is key to our ability to enlist the highest level of talent with annual internship costs exceeding $25,000 per intern. Build new opportunities for the next generation of world-class physician researchers by making a MATCHED gift by May 31st!