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Emmanouil Brilakis, MD, PHD, FACC, FAHA, FESC, FSCAI

Chairman, Center for Coronary Artery Disease

Dr. Brilakis is director of the Center for Complex Coronary Interventions at the Minneapolis Heart Institute® and chairman of the Center for Coronary Artery Disease at the Minneapolis Heart Institute Foundation.

After graduating from Lycee Leonin de Patissia, Dr. Brilakis received his medical degree from the National Kapodistrian University of Athens, Greece. He trained in internal medicine, cardiovascular diseases and interventional cardiology at the Mayo Clinic. He also completed a Masters in clinical research at the Mayo Clinic and a PhD in clinical research at the National Kapodistrian University of Athens, Greece. He served as director of the cardiac catheterization laboratories at VA North Texas Health Care System from 2004-2016. He was on the faculty of the University of Texas Southwestern Medical School from 2004-2018.

Dr. Brilakis leads a large clinical trial group investigating treatment of chronic total occlusions, prevention and treatment of saphenous vein graft disease, lipid lowering therapies, prevention and management of complications, intracoronary imaging, antiplatelet treatment optimization post coronary stenting, radiation safety in the catheterization laboratory, and development of novel technologies.

Dr. Brilakis has authored or co-authored more than 600 manuscripts and has written the Manual of CTO Interventions, now in its 2nd edition, and the Manual of PCI. He created the Manual of CTO Interventions and the Manual of PCI YouTube series. He is on the board of the Cardiovascular Innovations Foundation, an associate editor for Circulation and an editorial board member and reviewer for several journals and grant agencies. He is lecturing and proctoring at several institutions in the United States and abroad. 

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The Minneapolis Heart Institute Foundation® (MHIF) strives to create a world without heart and vascular disease. To achieve this bold vision, we are dedicated to improving the cardiovascular health of individuals and communities through innovative research and education.

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Register for our free Heart Valve Disease Awareness Day Event!

Heart Valve Disease Awareness Day 2025
Heart Valve Disease Awareness Day 2025

"From Basics to Breakthroughs: Heart Valve Health and Vitality" is a free-to-attend educational event designed to inform local community members about the latest breakthroughs in valvular heart disease. Join us on Saturday, February 22nd, at the Lafayette Club in Minnetonka Beach, MN.