Name: The Physiology Course
Start: 2025-06-05T07:00:00
Location: MacMillan Center

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Course Directors

Faculty

Agenda

Case & Abstract Competition

06/05/2025 07:00

Days

Hours

Mins

Secs

Until The Physiology Course Begins

The Minneapolis Heart Institute Foundation® (MHIF) and Allina Health Minneapolis Heart Institute®, in partnership with The American College of Cardiology - Minnesota Chapter®, are pleased to present The Physiology Course. Join us as we explore how to use coronary physiology for the assessment of epicardial coronary artery disease and the coronary microcirculation. This educational opportunity is an in-person experience that includes presentations, debates, discussions, hands-on training, and interactive live cases.

Dates: June 5-6, 2025
Location: MacMillan Center | 2800 10th Ave S, Minneapolis, MN

Our expert faculty will delve into the latest research and advancements in coronary physiology, including wire-based and wireless approaches, providing valuable insights for cardiovascular professionals and researchers alike to improve patient care. Don't miss the opportunity to join this inaugural coronary physiology course in the United States and deepen your understanding of the vital role that coronary physiology plays in modern PCI and the assessment of patients with coronary microvascular dysfunction.

Course Directors

Yader Sandoval, MD, FACC, FSCAI, FESC

Interventional Section | Allina Health Minneapolis Heart Institute
Co-Chairman, Center for Coronary Artery Disease | Minneapolis Heart Institute Foundation
Adjunct Associate Professor | Mayo Clinic College of Medicine and Science

Emmanouil Brilakis, MD, PhD, FACC, FAHA, FESC, FSCAI

Director, Center for Complex Coronary Interventions | Allina Health Minneapolis Heart Institute
Chairman, Center for Coronary Artery Disease | Minneapolis Heart Institute Foundation

Carlos Collet, MD, PhD

Codirector, Catheterization Laboratory | Cardiovascular Center OLV

Bernard De Bruyne, MD, PhD

Interventional Cardiologist | Cardiovascular Center OLV

Faculty

João Cavalcante, MD, FACC, FASE, FSCCT, FSCMR

Section Head, Cardiac Imaging | Allina Health Minneapolis Heart Institute
Director, Cardiovascular Imaging Research Center and Core Lab | Minneapolis Heart Institute Foundation
Inaugural Innovation Chair, Van Tassel Innovation Center | Minneapolis Heart Institute Foundation

William Fearon, MD

Professor of Medicine, Chief of the Interventional Cardiology Section | Stanford University School of Medicine
Chief of Cardiology Section | VA Palo Alto Health Care System

Sandeep Jalli, DO

Frank J. and Eleanor Maslowski Charitable Trust CHIP-CTO Fellow | Center for Coronary Artery Disease, Minneapolis Heart Institute Foundation, Allina Health Minneapolis Heart Institute

Nils P. Johnson, MD, MS

Professor of Medicine, Weatherhead Distinguished Chair of Heart Disease | McGovern Medical School at UTHealth

Morton J. Kern, MD

Professor of Medicine | University of California, Irvine
Chief of Cardiology | Long Beach Veterans Administration Medical Center

Claire E. Raphael, MBBS, PhD

Cardiologist, Assistant Professor, Senior Associate Consultant | Mayo Clinic

Jas Sara, MBChB, PhD

Interventional Cardiology Fellow
Allina Health Minneapolis Heart Institute

Arnold Seto, MD, MPA

Interventional Cardiologist, Past Chief of Cardiology | Long Beach VA Medical Center
Associate Clinical Professor | University of California, Irvine
Treasurer | Society of Cardiovascular Angiography and Interventions

Nathaniel R. Smilowitz, MD

Assistant Professor, Department of Medicine | New York University Grossman School of Medicine
Interventional Cardiologist | NYU Langone Health & VA New York

Karan Sud, MD

Interventional Cardiology Fellow | Allina Health Minneapolis Heart Institute

Jay Traverse, MD

Senior Consulting Cardiologist | Allina Health Minneapolis Heart Institute
Associate Professor of Medicine | University of Minnesota Medical School

R. Jay Widmer, MD, PhD

Interventional Cardiologist | Baylor Scott & White Health

Agenda

Agenda Day 1 | June 5, 2025

Day 1 - Session 1: Why? Moderators: Yader Sandoval, MD & Emmanouil Brilakis, MD, PhD Panelists: Bernard De Bruyne, MD, PhD; Carlos Collet, MD, PhD
0700-0745	Registration
0745-0800	Introduction \| Yader Sandoval, MD; Emmanouil Brilakis, MD, PhD; Bernard De Bruyne, MD, PhD; Carlos Collet, MD, PhD
0800-0812	Why Physiology? \| Yader Sandoval, MD
0812-0817	Q&A
0817-0829	How We Got to Now \| Bernard De Bruyne, MD, PhD
0829-0834	Q&A
0834-0846	Key Concepts \| Nils Johnson, MD, MS
0846-0851	Q&A
0851-0903	The Physiology Toolkit \| William Fearon, MD
0903-0908	Q&A
0908-0920	FFR \| Morton Kern, MD
0920-0925	Q&A
0925-0937	NHPR \| Emmanouil Brilakis, MD, PhD
0937-0942	Q&A
0942-0954	PPG \| Carlos Collet, MD, PhD
0954-1000	Q&A
1000-1030	Coffee Break
Day 1 - Session 2: Live Cases by the Allina Health Minneapolis Heart Institute Moderators: Carlos Collet, MD, PhD & Bernard De Bruyne, MD, PhD Panelists: William Fearon, MD & Morton Kern, MD
1030-1200	Live Cases 1 and 2 by the Allina Health Minneapolis Heart Institute \| Operators: Yader Sandoval, MD and Emmanouil Brilakis, MD, PhD
1200-1300	Lunch and Networking
Day 1 - Session 3: Non-Invasive and Wireless Physiology Moderators: William Fearon, MD & Morton Kern, MD Panelists: Arnold Seto, MD, MPA & Nils P. Johnson, MD, MS
1300-1312	CT-Based Coronary Physiology and Virtual PCI \| Yader Sandoval, MD
1312-1317	Q&A
1317-1329	Angiographic FFR \| Arnold Seto, MD, MPA
1329-1334	Q&A
1334-1346	Debate: PET for CMD \| Nils Johnson, MD, MS
1346-1358	Debate: CMFRI for CMD \| João L Cavalcante, MD
1358-1403	Q&A
1403-1410	Hands-On Explanation and Split into Small Groups
Day 1 - Session 4: Hands-On Breakout Sessions
1410-1710	Hands-On Breakout Sessions
1710-1730	Day 1 Wrap-Up and Transport to Reception
1800-2100	Conference Dinner Reception - All full-access attendees are invited to the faculty and attendee reception, at the Walker Art Center, 725 Vineland Place, Minneapolis, MN 55403. The reception will include time to connect with course faculty and colleagues, along with heavy hors d’oeurves/dinner options, wine and beer. Transportation will be provided between the course and the Walker, with a later shuttle returning to the Rand Towers Hotel.

Agenda Day 2 | June 6, 2025

Day 2 - Session 5: Coronary Microvascular Dysfunction - Part 1 Moderators: Carlos Collet, MD, PhD & Bernard De Bruyne, MD, PhD Panelists: Claire E. Raphael, MBBS, PhD & R. Jay Widmer, MD, PhD
0745-0800	Day 1 Recap \| Carlos Collet, MD, PhD and Bernard De Bruyne, MD, PhD
0800-0812	CFR \| Morton Kern, MD
0812-0817	Q&A
0817-0829	Bolus Thermodilution and IMR \| William Fearon, MD
0829-0834	Q&A
0834-0846	Continuous Thermodilution and MRR \| Bernard De Bruyne, MD, PhD
0846-0900	Q&A and Live Case Transition
Day 2 - Session 6: Live Cases by the Allina Health Minneapolis Heart Institute Moderators: William Fearon, MD & Morton Kern, MD Panelists: R. Jay Widmer, MD, PhD & Nathaniel R. Smilowitz, MD
0900-1030	Live Cases 3 and 4 by the Allina Health Minneapolis Heart Institute \| Operators: Yader Sandoval, MD and Emmanouil Brilakis, MD, PhD
1030-1100	Coffee Break
Day 2 - Session 7: Coronary Microvascular Dysfunction - Part 2 Moderators: Claire Raphael, MBBS, PhD & Nathaniel Smilowitz, MD, MS Panelists: William Fearon, MD & Carlos Collet, MD, PhD
1100-1112	Doppler-Based Assessment of CMD \| R. Jay Widmer, MD, PhD
1112-1117	Q&A
1117-1129	Acetylcholine Spasm Provocation \| Claire Raphael, MBBS, PhD
1129-1134	Q&A
1134-1146	Myocardial Bridging \| Nathaniel Smilowitz, MD, MS
1146-1151	Q&A
1151-1203	The Chest Pain Clinic \| Claire Raphael, MBBS, PhD
1203-1208	Q&A
1208-1220	Best FIT Abstract Presentation
1220-1230	Q&A
1230-1330	Lunch and Networking
Day 2 - Session 8: Lesion Subsets and Key Scenarios Moderators: Arnold Seto, MD, MPA Panelists: Yader Sandoval, MD, Emmanouil Brilakis, MD, PhD & R. Jay Widmer, MD, PhD
1330-1340	Serial Lesions: How-to \| Nils Johnson, MD, MS
1340-1345	Q&A
1345-1355	Physiology for Complex PCI \| Emmanouil Brilakis, MD, PhD
1355-1400	Q&A
1400-1410	Post-PCI Physiology \| Yader Sandoval, MD
1410-1415	Q&A
1415-1430	Coffee Break
Day 2 - Session 9: Therapies and Future Directions Panelists: Yader Sandoval, MD, Emmanouil Brilakis, MD, PhD, Carlos Collet, MD, PhD & Bernard De Bruyne, MD, PhD
1430-1440	Medical Therapy for CMD \| Nathaniel Smilowitz, MD, MS
1440-1445	Q&A
1445-1455	Microvascular Obstruction in STEMI \| Jay Traverse, MD
1455-1500	Q&A
1500-1510	Emerging Interventional Therapies \| R. Jay Widmer, MD, PhD
1510-1515	Q&A
1515-1525	Vulnerability: The Next Frontier in Coronary Physiology \| Carlos Collet, MD, PhD
1525-1530	Q&A
1530-1540	The 10 Commandments of Coronary Physiology \| Bernard De Bruyne, MD, PhD
1540-1545	Q&A
1545-1600	Conclusion and Final Remarks \| Yader Sandoval, MD; Emmanouil Brilakis, MD, PhD; Carlos Collet, MD, PhD; Bernard De Bruyne, MD, PhD

A photograph from the April 2024 CT-Guided PCI Course

Challenging Cases & Abstracts Competition

Fellows, Students, & Residents: Share your most challenging, innovative, or educational case or research abstract for a chance to present at The Physiology Course! Selected winners will have the opportunity to showcase their work during the program and receive a travel grant.

Case Competition

Please submit your most challenging, innovative or educational case for consideration in The Physiology Course 2025 Challenging Case Competition. Cases will be reviewed by course directors and winners will be selected to present during the conference program.

Read our FAQs to find out more!

Research Abstracts

The Research Abstracts gallery at The Physiology Course allows early-career researchers to share their work with their colleagues! Abstracts will be reviewed by course directors and winners will be selected to present during the conference.

Read our FAQs to find out more!