From Heartache to Heart Break: The Truth About Takotsubo Cardiomyopathy

Have you ever heard the phrase “died of a broken heart”? While it might sound poetic, broken heart syndrome, or Takotsubo cardiomyopathy, is a very real—and sometimes dangerous—condition. At the Minneapolis Heart Institute Foundation (MHIF), our research physicians from Allina Health Minneapolis Heart Institute have been at the forefront of research and treatment for this unique cardiac disorder.

See a recent interview that aired on FOX 9/KMSP with Dr. Scott Sharkey, MHIF Chief Medical Officer and Cardiologist at Allina Health Minneapolis Heart Institute.

Dr. Sharkey explains that broken heart syndrome is triggered by sudden emotional or physical stress, potentially related to over-release of the stress hormone, epinephrine. When affected, the heart’s main pumping chamber temporarily changes shape and can’t function properly, leading to sudden chest pain, trouble breathing, and other symptoms that may feel just like those of a heart attack. However, unlike a typical heart attack, broken heart syndrome does not result from blocked arteries—a distinction that’s vital for proper diagnosis and care. 

MHIF Research has revealed key warning signs in the setting of an intense emotional event or physical illness:

• Chest pain or pressure
• Shortness of breath not explained by exertion
• Feeling faint, weak, or experiencing dizziness

Early recognition and medical attention are crucial, as the condition can be life-threatening in some cases. Thankfully, most people fully recover with appropriate care, but prompt evaluation is essential.

Learn more about heart research from Minneapolis Heart Institute Foundation.