Clinical Research Studies
Hope for Patients
Our research offers hope for current patients and opportunities to make a difference for future patients. We explore every area of cardiovascular care. Ask your doctor about active MHIF studies that match your treatment needs.
Benefits of Research
Be More Active
Take a more active role in your own health care.
Potential to Unlock More Options
You may gain access to investigational treatments and medications.
Make a Contribution
Help find a new and better way to treat people with your condition.
Search for research studies
ALIGN ARStudy Investigator:
Dr. Paul Sorajja
About the Study:To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may include fatigue and shortness of breath. The preferred treatment for severe aortic regurgitation is aortic valve replacement surgery. Condition:
Valvular Disease (Heart Valve Disease), Aortic Regurgitation
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Evolut EXPAND llStudy Investigator:
Dr. Paul Sorajja
About the Study:Obtain safety and effectiveness data to support indication expansion for the Medtronic TAVR System to include patients with moderate, AS. Condition:
Valvular Disease (Heart Valve Disease), Moderate Aortic Valve Stenosis
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GenePHIT/ASK-CHF 2Study Investigator:
Dr. Jay Traverse
About the Study:This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single dose of AB-1002, administered via antegrade intracoronary artery infusion, in males and females age >18 years with non-ischemic cardiomyopathy and NYHA Class III symptoms of HF. Subjects will be randomized into one of three treatment groups in a 1:1:1 Condition:
Congestive Heart Failure
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OPTIMIZER PASStudy Investigator:
Dr. Jay Sengupta
About the Study:The OPTIMIZER Smart Post-Approval Study is a prospective, multi-center, non-randomized, single arm open label study of 620 subjects receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA functional class III symptoms and a left ventricular ejection fraction of 25-45% Condition:
Heart Failure
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AIM HIGHerStudy Investigator:
Drs. Mike Samara & Jay Sengupta
About the Study:The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤60%. Condition:
Heart Failure
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