Valve Science Center
Professional Resources
The Valve Science Center is a world-class research and education center for heart valve disease.
As a world leader in cardiac valve disease research, we actively participate in major clinical trials and conduct research pursued by leading physicians to understand valve disease and apply new treatment, diagnosis or monitoring methods. We are committed to translating heart valve disease research findings, implementing the learnings into routine clinical practice and widely sharing the information nationally and globally.
Leading the way in improving care and outcomes for valve patients, we are are recognized for notable “firsts”, including:
• First implant in world’s first pivotal trial (large study used to seek regulatory approval for the device) to evaluate a new approach for repairing leaky tricuspid heart valves — 2019
• First-in-human therapy of tricuspid regurgitation with the TriClip — 2017
• First-in-human therapy of severe mitral annular calcification using the Tendyne mitral prosthesis — 2017
• First-in-human therapy of hypertrophic cardiomyopathy with MitraClip — 2016
• First transcatheter mitral valve replacement in the U.S. with the Tendyne bioprosthetic mitral valve — 2015
– The center is a world-class leader in mitral valve replacement and remains the most experienced site in the world
• First-in-human therapy with the Myocor device for treatment of mitral regurgitation — 2008



Valvular Heart Health Lectures from MHIF Grand Rounds
Watch recordings or view slides from past lectures on heart valve disease and related topics.
April 19, 2021 • TAVR in TAVR, the future is here! by Muhammad Hammadah, MD (Slides)
January 18, 2021 • Journey with Transcatheter Valves by Vinayak Bapat, MD (Slides) (Recording)
October 12, 2020 • Mitral valve prolapse – when does it stop being benign? by Iulia Tulai, MD, Cardiology Fellow, Minneapolis Heart Institute® at Abbott Northwestern Hospital & Hennepin Healthcare (Slides) (Recording)
September 14, 2020 • The Conundrum of Functional Mitral Regurgitation by Maurice Enriquez-Sarano, MD (Slides) (Recording)
April 13, 2020 • Mitral Valve Surgery by Robert J Steffen, MD (Slides) (Recording)
January 20, 2020 • Update of Tricuspid Regurgitation: Evaluation and Treatment by Anene Ukaigwe, MB, BS (Slides) (Recording)
October 14, 2019 • Structural Heart Update 2019 by Paul Sorajja, MD (Slides) (Recording)
September 9, 2019 • Health Care Disparities in Structural Heart Disease – TVINCITIES Update by Mario Gössl, MD, PhD (Slides) (Recording)
April 22, 2019 • Multimodality Imaging for Valvular Disease – In Whom, When and Why? by João L. Cavalcante, MD, FACC, FSCMR, FSCCT (Slides) (Recording)
December 17, 2018 • The intersection of heart failure and structural cardiology by Peter Eckman, MD, FACC, FHFSA and Paul Sorajja, MD (Slides) (Recording)
January 22, 2018 • Transcatheter Valve Therapy (TVT) 2018 by Paul Sorajja, MD (Slides) (Recording)
Find more MHIF Grand Round Lectures here >>
View Recent Valve Science Center Publications
MHIF’s valve team has authored hundreds of papers and presents frequently at national and international conferences. Read some of the latest publications from our team below.
May 2021: Prevalence and Implications of Junctional Rhythm During Transcatheter Aortic Valve Replacement
April 2021: Importance of Myocardial Fibrosis in Functional Mitral Regurgitation: From Outcomes to Decision-Making
April 2021: Editorial: The Art of Balancing Functional Mitral Regurgitation Reduction and Gradients After TEER
April 2021: MitraClip After Failed Surgical Mitral Valve Repair – An International Multicenter Study
April 2021: Left Ventricular Scar Burden as a Modulator of Risk in Functional Mitral Regurgitation
April 2021: Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations
March 2021: Proposal for a Standard Echocardiographic Tricuspid Valve Nomenclature
Feb 2021: Transcatheter mitral valve repair in a patient with prior atrial septal defect occlusion
Feb 2021: Unveiling outcomes in coexisting severe aortic stenosis and transthyretin cardiac amyloidosis
Feb 2021: Natural history observations in moderate aortic stenosis
Jan 2021: Outcomes of percutaneous and surgical pulmonary valve implantation
Jan 2021: Imaging for Tricuspid Valve Repair and Replacement
Jan 2021: Assessment of aortic bioprosthetic valve fracture by Computed Tomography Angiography
Jan 2021: Transcatheter Edge-to-Edge Repair for Treatment of Tricuspid Regurgitation
Jan 2021: Imaging for Native Mitral Valve Surgical and Transcatheter Interventions
Jan 2021: Edge-to-edge repair: past challenge, current case selection and future advances

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