Research Study: DESIFOR
Condition:
statin-eligible patients
Study Sponsor: MHIF
Study Investigator: Michael Miedema, MD
Study Contact: Christine Majeski
christine.majeski@allina.com
612-863-3546
Every research study comes with its own unique risks and benefits; the study team will assess whether you’re an eligible candidate and ensure you’re provided with all the information you need to decide if participating is right for you.

About this Study:

This study will enroll patients who previously were not able to tolerate being on a statin medication due to muscle-related side effects. Research has shown that many people who have muscle symptoms on statin therapy do not experience the same side effects if they try it again later. This study is part of a larger effort to: See how common it is for patients to still be intolerant of statin medication after trying it a second time; and For those patients who do tolerate being on a statin after trying it a second time, see how common it is for them to still be taking the statin 3 months after completing the main part of the study.

Patients who agree to participate will be given a 5 month randomly allocated supply of statin and placebo and track their symptoms weekly.

Eligibility Criteria:

  • Adults age 21-75 years old
  • Statin eligible according to the 2013 ACC/AHA cholesterol guidelines, including individuals with:
    • Known ASCVD
    • Diabetes
    • LDL-C > 190mg/dl
    • 10-year ASCVD risk >7.5%
  • Statin intolerant
    • Defined by discontinuation of at least 2 separate statins due to potential musculoskeletal side effects

Interested in participating in this study?

Reach out to the study contact directly, or fill out this form and we will contact you and assess whether you are an eligible candidate!