Clinical Research Studies
We do research across every area of cardiovascular care. Our research offers hope for patients, options to discuss with your doctor, and opportunities to make a difference for future patients. See the search below for a list of our active and enrolling clinical research studies and see if you may qualify to participate.
Benefits of Research
Be More Active
Take a more active role in your own health care.
Potential to Unlock More Options
You may gain access to investigational treatments and medications.
Make a Contribution
Help find a new and better way to treat people with your condition.
Search for research studies
SOLVE-CRTStudy Investigator:
Jay Sengupta, MD
About the Study:This study is a prospective, multi-center, pivotal trial to study the safety and efficacy of the WiSE-CRT System for Cardiac Re-synchronization Therapy. The WiSE-CRT System is an implantable cardiac pacing system capable of delivering pacing energy to the left ventricle of the heart without using a pacing lead. Condition:
Heart Failure
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ATTR CMStudy Investigator:
Mosi Bennett, MD
About the Study:To evaluate the efficacy of AKCEA-TTR-LRx compared to placebo for 120 weeks in patients with ATTR-CM receiving available standard of care (SoC). Condition:
Cardiomyopathy
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TIMI 68Study Investigator:
Mosi Bennett, MD
About the Study:This is an international, multicenter, parallel-group, randomized, double-blind, placebo-controlled trial in patients with heart failure with reduced ejection fraction (left ventricular ejection fraction [LVEF] ≤40%) who have been stabilized during hospitalization for acute heart failure, evaluating the effect of in-hospital initiation of dapagliflozin versus placebo on the clinical outcome of cardiovascular death or worsening heart failure. Condition:
Heart Failure
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TAMBE AAAStudy Investigator:
Jesse Manunga, MD
About the Study:Prospective, non-randomized, multicenter study with two independent arms: 1) Primary Study Arm - TAAA and Pararenal aneurysms requiring only TAMBE System. Hypothesis-driven analysis. 2) Secondary Study Arm - TAAA requiring TAMBE System and CTAG Device(s). Non hypothesis-driven analysis. Condition:
Other
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PREVENTABLEStudy Investigator:
Sandy Oberembt, PA
About the Study:PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events. Condition:
Other
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