Center for Coronary Artery Disease 

Professional Resources

The Center for Coronary Artery Disease is strongly positioned for success through:  

  • A partnership with 70+ cardiologists who see more than 31,000 patients at nearly 57,000 clinic visits each year at Abbott Northwestern Hospital and 36 outreach sites.
  • An exceptionally large and diverse patient experience, complete with data contained within the electronic medical record as part of Allina Health.
  • A proven track record of dissemination, publishing 63 journal articles (including peer-reviewed) in 2019, along with 25 poster presentations and 48 invited presentations at 22 meetings (15 in the U.S. and 7 internationally.

Our CCAD Research

We are making the impossible possible through innovative research and education around treatment approaches for coronary artery disease cases. Check out our research and resources below.

CTO Manual
A searchable database of complex CTO cases. Resources compiled by faculty at the Center for Coronary Artery Disease.
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PCI Manual
A searchable case library of non-CTO coronary interventions compiled by faculty at the Center for Coronary Artery Disease.
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PROGRESS-CTO

PROGRESS-CTO is an ongoing contemporary, multi-center global registry of more than 7,000 CTO-PCIs at 50 participating centers, with a goal to provide novel insights into the most complex type of CTO-PCIs through rigorous study of techniques and outcomes across a varied group of operators and medical practices.

REBIRTH
This is a randomized prospective trial that will compare Radial artery access to state-of-the-art Femoral artery access for Cardiac Catheterization and PCI procedures. The objective of this trial is to help determine the optimal method for obtaining arterial access in various clinical settings and improve patient outcomes.
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PROGRESS-Bifurcation Registry

Approximately 20% (1 in 5) coronary artery lesions involves a branching point (bifurcation). Recanalizing bifurcation lesions can be challenging because the branching artery may become obstructed or completely occluded during the procedure. The recently launched PROGRESS-Bifurcation registry will provide novel insights on the current state and future directions on coronary bifurcation interventions.

CCAD Presentations Map

We are proud to share research and education with peers around the world. Take a look where we’ve presented our research below!

Recent Publications

MHIF’s CCAD team has authored hundreds of papers and presents frequently at national and international conferences. Read some of the latest publications from our team below.

Dec 2020: Technical and procedural outcomes of the retrograde approach to chronic total occlusion interventions

Nov 2020: Impact of Successful Chronic Total Occlusion Percutaneous Coronary Interventions on Subsequent Clinical Outcomes 

Nov 2020: Impact of Chronic Total Occlusion Revascularization on Left Ventricular Function Assessed by Cardiac Magnetic Resonance

Nov 2020: Outcomes of subintimal plaque modification in chronic total occlusion percutaneous coronary intervention 

Oct 2020: Patient Radiation Dose During Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry

Oct 2020: Systematic review and meta-analysis of short-term outcomes with drug-coated balloons vs. stenting in acute myocardial infarction

Oct 2020: Complications of chronic total occlusion percutaneous coronary intervention

August 2020: Follow-up Outcomes After Chronic Total Occlusion Percutaneous Coronary Intervention in Patients With and Without Prior Coronary Artery Bypass Graft Surgery: Insights From the PROGRESS-CTO Registry

August 2020: Outcomes of Percutaneous Coronary Intervention for In-Stent Chronic Total Occlusions: Insights from the PROGRESS-CTO Registry 

July 2020: Computed Tomography Angiography Co-Registration with Real-Time Fluoroscopy in Chronic Total Occlusion Percutaneous Coronary Interventions

July 2020: Latest developments in chronic total occlusion percutaneous coronary intervention

July 2020: Complications and failure modes of coronary microcatheters: Insights from the manufacturer and user facility device experience (MAUDE) database 

June 2020: The Impact of Novel X-Ray Systems and X-Ray System Optimization on Patient Radiation Dose Administered During Cardiac Catheterization 

June 2020: Outcomes with combined laser atherectomy and intravascular brachytherapy in recurrent drug-eluting in-stent restenosis

June 2020: Equipment utilization in chronic total occlusion percutaneous coronary interventions: Insights from the PROGRESS-CTO registry

April 2020: Temporal Trends in Chronic Total Occlusion Percutaneous Coronary Interventions: Insights From the PROGRESS-CTO Registry 

April 2020: Retrograde Approach to Chronic Total Occlusion Percutaneous Coronary Intervention  

April 2020: Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention in Patients With Prior Bypass Surgery  

April 2020: Sequential complications troubleshooting in percutaneous coronary intervention: Managing wire entrapment and coronary dissection

March 2020: The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)  

Feb 2020: Primary orbital atherectomy for treating a heavily calcified balloon uncrossable lesion   

Feb 2020: Retrograde Chronic Total Occlusion Percutaneous Coronary Intervention via Saphenous Vein Graft

Jan 2020: Impact of concomitant treatment of non-chronic total occlusion lesions at the time of chronic total occlusion intervention

Read more publications on PubMed based on authors:  

Dr. Emmanouil Brilakis 

Dr. Nicholas Burke 

Dr. Bavana V. Rangan  

Dr. Judit Karacsonyi 

Dr. Evangelia Vemmou  

Dr. Ilias Nikolakopoulos  

Past Publications  

2018 In Press
2017 In Press
Editorials
Book Chapters

Grand Rounds Presentations

November 23, 2020  •  CT imaging of coronary artery plaque: Substrate-based approach to coronary artery disease by Victor Cheng, MD; (Slides) (Recording)

November 9, 2020  •  AHA Preview
Contemporary In-Hospital Outcomes of Chronic Total Occlusion Interventions: Update from the PROGRESS-CTO Multicenter International Registry and Outcomes of Patients with ST Elevation Myocardial Infarction and History of Prior Coronary Artery Bypass Graft Surgery by Judit Karacsonyi, MD, PhD, Research Fellow, Minneapolis Heart Institute Foundation®; (Slides) (Recording)

Radial Versus Femoral Access For Coronary Procedures In Patients With Prior Coronary Artery Bypass Grafting Surgery: An Updated Study-level Meta-analysis by Ilias Nikolakopoulos, MD, Research Fellow, Minneapolis Heart Institute Foundation®; (Slides) (Recording)

May 11, 2020  •  Complete Revascularization in Patients with Multi-Vessel Coronary Artery Disease: Is the Story COMPLETE? by Mohamed A Omer, MD, MSc, Interventional Cardiology Fellow, Minneapolis Heart Institute® at Abbott Northwestern Hospital; (Slides) (Recording)

October 14, 2019 • Engaging MHIF Research: Structural Heart, Electrophysiology and Complex Coronary Artery Disease – Current CCAD Studies by Emmanouil S. Brilakis, MD, PhD, Director, Center for Complex Coronary Artery Disease; (Slides) (Recording)

April 15, 2019 • Update on Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention by Emmanouil S. Brilakis, MD, PhD, Director, Center for Complex Coronary Artery Disease; (Slides) (Recording)

More Grand Rounds

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