Complex Coronary Artery Disease
Science Center

Making the impossible possible through innovative research and education around treatment approaches for the most complex of coronary artery disease cases.

Minneapolis Heart Institute Foundation® (MHIF) has built its reputation as one of the nation’s most distinguished champions of coronary artery disease (CAD) research and treatment. Under the leadership of Dr. Emmanouil Brilakis, the Complex Coronary Artery Disease Science Center works to decrease the burden of CAD through research, innovation and education

MHIF’s Complex CAD Science Center is strongly positioned for success through:

  • A partnership with 70+ cardiologists who see more than 31,000 individual patients at nearly 57,000 clinic visits each year at Abbott Northwestern Hospital (ANW) and 36 outreach sites
  • An exceptionally large and diverse patient experience complete with data contained within the electronic medical record as part of Allina Health
  • A proven track record of dissemination, publishing 188 manuscripts in 2017 in peer-reviewed journals and presenting novel

Research

Progress-CTO

PROspective Global Registry for the Study of CTO Interventions. Learn more from the multi-center registry of Chronic Total Occlusion Precutaneous Coronary Interventions.

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ASAP SVG

The pilot trial for Alirocumab for Stopping Atherosclerosis Progression in Saphenous Vein Grafts aims to improve the CABG patients’ quality and duration of life, reduce the need for repeat revascularization procedures, and potentially reduce their healthcare costs.

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Shine CTO

SHam-controlled INtErvention to Improve Quality of Life in CTOs (SHINE-CTO Trial). Provides novel insights into the most complex type of percutaneous coronary interventions, i.e. treatment of coronary chronic total occlusions (100% blockages that are >3 months old).

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REBIRTH

This is a randomized prospective trial that will compare Radial artery access to state-of-the-art Femoral artery access for Cardiac Catheterization and PCI procedures. The objective of this trial is to help determine the optimal method for obtaining arterial access in various clinical settings and improve patient outcomes.

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Education

Patients

By collaborating with other cardiology fields, such as non-invasive imaging, advanced heart failure and cardiac surgery, patients can be successfully treated, improving their quality, and often quantity, of life.

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Professionals

With several ongoing research and education projects, the CCAD Science Center is having a significant impact on the health of patients with complex coronary artery disease around the world.

CTO Manual 
PCI Manual
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News & Events

News

Dr. Brilakis Featured in Allina Health’s Annual Report

Dr. Manos Brilakis, Director of MHIF's Complex Coronary Artery Disease Science Center, was featured in...

News

MHIF Well Represented at CRT2019

Several researchers from Minneapolis Heart Institute Foundation represented at CRT2019 in Washington D.C. the first...

News

CCAD Research Scholars Named Finalists in CTO2019 Case Competition

The 2019 Chronic Total Occlusion (CTO) Summit featured a Challenging Case Competition sponsored by the...

Dr. Brilakis Featured in Allina Health’s Annual Report

Dr. Manos Brilakis, Director of MHIF's Complex Coronary Artery Disease Science Center, was featured in Allina Health's 2018 Annual Report. “Our culture at MHI® and MHIF is one...

MHIF Well Represented at CRT2019

Several researchers from Minneapolis Heart Institute Foundation represented at CRT2019 in Washington D.C. the first weekend in March. Amongst the team, there was a total of 43...

CCAD Research Scholars Named Finalists in CTO2019 Case Competition

The 2019 Chronic Total Occlusion (CTO) Summit featured a Challenging Case Competition sponsored by the Cardiovascular Research Foundation (CRF).  The CRF tasked attendees with submitting the most...

Our Team

The Complex Coronary Artery Disease Science Center is an international leader in research and education on complex coronary artery disease.

Meet the team of physicians, scholars and staff
who help save lives every day.

Meet the Team

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