April 3, 2020
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute myocardial infarction (heart attack), often afflicting younger women without coronary atherosclerosis (build up in the arteries). Primary percutaneous coronary intervention (PCI) for management of SCAD has low reported initial success rates and high reported rates of in-stent thrombosis and restenosis. Emergent PCI is necessary in some circumstances, and outcomes of these patients is unknown.
In a new study funded by SCAD Research Inc, researchers from the Minneapolis Heart Institute Foundation® (MHIF) compared the long-term outcomes for 55 patients treated with revascularization (including attempted) at initial angiogram with 63 non-revascularized patients at initial angiogram.
“Our data supports that revascularization can be an appropriate management strategy for high risk SCAD patients, but initially higher rates of SCAD complications should be anticipated,” Dr. Thaler said.
Watch a MHIF-recorded presentation on the research findings*, “Long-Term Outcomes After Emergency Revascularization For Spontaneous Coronary Artery Dissection,” from Dr. Christina Thaler, Cardiology Fellow at Minneapolis Heart Institute® and MHIF researcher here.
*Note: These results represent unpublished findings. Dr. Thaler also presented on these findings at the American College of Cardiology (ACC) 2020 World Congress, which was held virtually on March 28-30, 2020.
Related SCAD research and provider resources from MHIF:
- Research Shows Reperfusion with Primary Percutaneous Coronary Intervention is Successful in Most STEMI-SCAD Patients, published in the September 2019 issue of the Journal of the American College of Cardiology
- MHIF Grand Rounds Presentation, December 2, 2019 Spontaneous Coronary Artery Dissection: Unraveling an Enigma by Christina Thaler, MD, PhD (Slides) (Recording)
About Spontaneous Coronary Artery Dissection (SCAD)
SCAD is an increasingly recognized condition that occurs when there is a spontaneous tear in an artery that is apparently healthy.
- The causes of SCAD are uncertain
- Nearly 90 percent of SCAD patients are women and it is afflicting a growing number of women in their 40s and 50s
- SCAD is the #1 cause of heart attack among younger women
SCAD is an important area of research as part of the Penny Anderson Women’s Cardiovascular Center at MHIF.
MHIF has a database assembled of all SCAD patients who are being followed at Abbott Northwestern Hospital (part of one of the largest health systems in Minnesota) over the past 20 years; there is a team of 5 cardiologists and 5 research scientists dedicated to this effort. MHIF has published positive experience of emergency treatment of SCAD heart attacks with coronary stents and coronary bypass grafting (Journal of the American College of Cardiology, September 2019).