Current Studies

SENECA: A Phase I

First-in-Human, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study of the Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Cancer Survivors with Anthracycline-Induced Cardiomyopathy. Study Sponsor: University of Texas School of Public Health....

CONCERT-HF

Study Sponsor: The CCTRN Data Coordinating Center, University of Texas-Houston School of Public Health Principal Investigator: Jay H. Traverse, MD Study Synopsis: Heart failure is a serious and common condition. It is a condition in which the heart muscle does not...

DREAM-HF-1

Title: DREAM-HF-1 Study. A Phase III Double-Blind, Sham-procedure controlled, Parallel-group Efficacy and Safety Study of Allogeneic Mesenchymal Precursor Cells (rexlemestrocoel-l) in Patients with Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of...

ALLSTAR

Title: Randomized, Double-Blinded, Placebo-Controlled Phase I/II Study of the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells in Patients With a Myocardial Infarction and Ischemic Left Ventricular Dysfunction (Allogeneic Heart...

LOWER AEGR 733-025

Study Title: LOWER AEGR 733-025 Condition: Homozygous Familial Hypercholesterolemia Study Purpose: This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety...

BIOFLOW-V

Study Title:  BIOFLOW-V Condition:  Coronary Artery Disease Study Purpose:  BIOFLOW-IV is a prospective, international, multicenter, randomised controlled trial. The purpose of this trial is to compare the Biotronik Orsiro drug eluting stent system with the Xience...

REPRISE III

Study Title:  REPRISE III Condition:  Severe Aortic Stenosis Study Purpose:  The objective of this study is to evaluate the safety and effectiveness of the Lotus™ Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with calcific,...

CS-03 Tendyne

Study Title:  CS-03 Tendyne Condition:  Severe Mitral Regurgitation Study Purpose:  The purpose of this study is to generate initial insights into the safety and performance of the Tendyne Mitral Valve System. The study includes adult patients with symptomatic mitral...

PERIGON

Study Title:  PERIGON Condition:  Aortic Valve Replacement Study Purpose:  To evaluate the safety and effectiveness of the Model 400 aortic valve bioprosthesis. Principal Investigators:  Vibhu Kshettry, MD Co-Investigators:  Saied Farivar, MD; Benjamin Sun, MD...